000 02478 a2200337 4500
003 NISER
005 20260116163407.0
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020 _a9783030623869
_qPaperback
040 _aNISER LIBRARY
_beng
_cNISER LIBRARY
082 0 4 _a57.087.1
_bWIN-S
100 1 _aWinkelmann, Stefanie
245 1 0 _aStochastic dynamics in computational biology
260 _aCham, Switzerland :
_bSpringer,
_c2020.
300 _axviii, 272 pages :
_billustrations (55 illus., 46 illus. in color.) ;
_c23 cm.
490 _aFrontiers in applied dynamical systems: reviews and tutorials,
_x2364-4532 ;
_vv. 8
504 _aIncludes bibliographical references and index.
520 _aThe aim of this book is to provide a well-structured and coherent overview of existing mathematical modeling approaches for biochemical reaction systems, investigating relations between both the conventional models and several types of deterministic-stochastic hybrid model recombinations. Another main objective is to illustrate and compare diverse numerical simulation schemes and their computational effort. Unlike related works, this book presents a broad scope in its applications, from offering a detailed introduction to hybrid approaches for the case of multiple population scales to discussing the setting of time-scale separation resulting from widely varying firing rates of reaction channels. Additionally, it also addresses modeling approaches for non well-mixed reaction-diffusion dynamics, including deterministic and stochastic PDEs and spatiotemporal master equations. Finally, by translating and incorporating complex theory to a level accessible to non-mathematicians, this book effectively bridges the gap between mathematical research in computational biology and its practical use in biological, biochemical, and biomedical systems.
650 0 _aBiomathematics
650 0 _aDynamical systems
650 0 _aMathematical and Computational Biology
650 0 _aStochastic processes
650 0 _aSystems biology
650 0 _aDynamical Systems and Ergodic Theory
650 0 _aGene expression
650 0 _aChemical reaction network
700 1 _aSchütte, Christof
856 4 1 _3Table of contents
_uhttps://link.springer.com/content/pdf/bfm:978-3-030-62387-6/1
856 4 1 _3Reviews
_uhttps://www.goodreads.com/book/show/70749348-stochastic-dynamics-in-computational-biology?ref=nav_sb_ss_1_13#CommunityReviews
942 _cBK
_2udc
999 _c36765
_d36765