000			03303nam a22003497a 4500
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005			20250321142808.0
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020			_a9783030657673
040			_aNISER LIBRARY _beng _cNISER LIBRARY
082			_a616-006 _bLE-H
245			_aHeterogeneity of cancer metabolism
250			_a2nd edition
260			_aCham, Switzerland : _bSpringer, _c2021.
300			_axxiii, 271 pages.
490			_aAdvances in experimental medicine and biology, _vvolume 1311 _x0065-2598 ;
504			_aIncludes bibliographical references and index.
520			_aThis open access volume will introduce recent discoveries in cancer metabolism since the publication of the first edition in 2018, providing readers with an up-to-date understanding of developments in the field. Genetic alterations in cancer, in addition to being the fundamental drivers of tumorigenesis, can give rise to a variety of metabolic adaptations that allow cancer cells to survive and proliferate in diverse tumor microenvironments. This metabolic flexibility is different from normal cellular metabolic processes and leads to heterogeneity in cancer metabolism within the same cancer type or even within the same tumor. In this book, the authors delve into the complexity and diversity of cancer metabolism and highlight how understanding the heterogeneity of cancer metabolism is fundamental to the development of effective metabolism-based therapeutic strategies for cancer treatment. Deciphering how cancer cells utilize various nutrient resources will enable clinicians and researchers to pair specific chemotherapeutic agents with patients who are most likely to respond with positive outcomes, allowing for more cost-effective and personalized cancer treatment. This book has four major parts. Part one will cover the basic metabolism of cancer cells, followed by a discussion of the heterogeneity of cancer metabolism in part two. Part three addresses the relationship between cancer cells and cancer-associated fibroblasts, and the new part four will explore the metabolic interplay between cancer and other diseases. This new section makes the book unique from other texts currently available on the market. The second edition will be useful for cancer metabolism researchers, cancer biologists, epidemiologists, physicians, health care professionals in related disciplines, policymakers, marketing and economic strategists, among others. It may also be used in courses such as intro to cancer metabolism, cancer biology, and related biochemistry courses for undergraduate and graduate students.
650			_aBiomedicine
650			_aCancer _xTreatment
650			_aCancer cells _xMetabolism
650			_aCancer cells _xMolecular aspects
650			_aCancer research
650			_aEpigenetics and oncometabolites
650			_aGlutamine metabolism
650			_aMedical _xOncology
700			_aLe, Anne _eeditor
856			_3Electronic version _uhttps://link.springer.com/book/10.1007/978-3-030-65768-0
856			_3Table of contents _uhttps://link.springer.com/content/pdf/bfm:978-3-030-65768-0/1
856			_3Reviews _uhttps://www.goodreads.com/book/show/70489134-the-heterogeneity-of-cancer-metabolism#CommunityReviews
942			_2udc _cBK
999			_c35928 _d35928