000			01990nam a22002897a 4500
003			OSt
005			20250122145241.0
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020			_a9783039213276
040			_aNISER LIBRARY _beng _cNISER LIBRARY
082			_a576.311.347 _bHAA-M
245			_aMitochondrial dysfunction in aging and diseases of aging
260			_aSwitzerland : _bMDPI, _c2019
300			_aix, 256p.
520			_aThis collection of review articles authored by international experts pulls together current information about the role of mitochondria in aging and diseases of aging. Mitochondria are vitally important cellular organelles and undergo their own aging process becoming less efficient in aged animals including humans. These changes have wide-ranging significance contributing to immune dysfunction (autoimmunity and immune deficiency), inflammation, delayed healing, skin and retinal damage, cancer and most of the degenerative diseases of aging. Mitochondrial aging predisposes to drug toxicity in the geriatric population and to many of the features of normal aging. The research detailed in this book summarizes current understanding of the role of mitochondria in the complex molecular changes of aging, moving on to specific diseases of aging. Mitochondrial dysfunction is an important target for development of treatments for aging and disease. The last article details how exercise is a treatment and combats many features of the aging process.
650			_aAdaptive immunity
650			_aAge-related diseases
650			_aAge-related macular degeneration
650			_aAgeing
650			_aAlzheimers disease
650			_aInflammation
650			_aCell danger response
650			_aNeurodegenerative disease
700			_aHaas, Richard H. _eed.
856			_3Reviews _uhttps://www.goodreads.com/book/show/56382788-mitochondrial-dysfunction-in-aging-and-diseases-of-aging?ref=nav_sb_ss_1_13#CommunityReviews
942			_2udc _cBK
999			_c35547 _d35547