000			05565cam a2200541Ia 4500
001			ocn173973284
003			OCoLC
005			20141103172222.0
006			m o d
007			cr cnu---unuuu
008			071010s2007 cauaf ob 001 0 eng d
040			_aN$T _beng _cN$T _dYDXCP _dBTCTA _dOCLCQ _dCUS _dOCLCQ _dAZU _dUMC _dOCLCQ _dOPELS _dOCLCQ _dOPELS _dOCLCF _dVVL _dKUK
019			_a166230819 _a173240431 _a179791190
020			_a9780080551050 (electronic bk.)
020			_a008055105X (electronic bk.)
020			_a9780123739223 (electronic bk.)
020			_a0123739225 (electronic bk.)
029	1		_aAU@ _b000044186537
035			_a(OCoLC)173973284 _z(OCoLC)166230819 _z(OCoLC)173240431 _z(OCoLC)179791190
050		4	_aQH450.25 _b.R53 2007eb
050		4	_aQP601 _b.M49 vol. 424
072		7	_aSCI _x049000 _2bisacsh
082	0	4	_a572.8/845 _222
049			_aTEFA
245	0	0	_aRNA editing _h[electronic resource] / _cedited by Jonatha M. Gott.
260			_aSan Diego, Calif. : _bAcademic Press/Elsevier, _cc2007.
300			_a1 online resource (xlv, 544 p., [10] p. of plates) : _bill. (some col.)
490	1		_aMethods in enzymology, _x0076-6879 ; _vv. 424
505	0		_aIsolation and compositional analysis of trypanosomatid editosomes / A.K. Panigrahi ... [et al.] -- Uridine insertion/deletion editing activities / J. Carnes ... [et al.] -- RNA editing uridylyltransferases of trypanosomatids / R. Aphasizhev ... [et al.] -- Isolation of RNA binding proteins involved in insertion/deletion editing / M. Pelletier ... [et al.] -- RNA-protein interactions in assembled editing complexes in trypanosomes / J. Cruz-Reyes ... [et al.] -- Strategies of kinetoplastid cryptogene discovery and analysis / D.A. Maslov ... [et al.] -- RNA editing in Physarum mitochondria: Assays and biochemical approaches / E.M. Byrne ... [et al.] -- Computational approaches to insertional RNA editing / R. Bundschuh ... [et al.] -- Evolution of RNA editing sites in the mitochondrial small subunit rRNA of the Myxomycota / U. Krishnan ... [et al.] -- Analysis of 5'- or 3'-terminal trna editing: Mitochondrial 5' tRNA editing in Acanthamoeba castellanii as the exemplar / A.J. Lohan ... [et al.] -- Comparative genomic and bioinformatic approaches for the identification of new adenosine-to-inosine substrates / J. Sixsmith ... [et al.] -- Genetic approaches to studying adenosine-to-inosine RNA editing / J.E.C. Jepson ... [et al.] -- A method for finding sites of selective adenosine deamination / J. Ohlson ... [et al.] -- Purification and assay of ADAR activity / L.P. Keegan ... [et al.] -- Large-scale overexpression and purification of ADARs from Saccharomyces cerevisiae for biophysical and biochemical studies / M.R. Macbeth ... [et al.] -- Mouse models to elucidate the functional roles of adenosine-to-inosine editing / E.Y. Rula ... [et al.] -- Probing adenosine-to-inosine editing reactions using RNA-containing nucleoside analogs / O. Maydanovych ... [et al.] -- Measuring editing activity and identifying cytidine-to-uridine mrna editing factors in cells and biochemical isolates / H.C. Smith ... [et al.] -- Mouse models as tools to explore cytidine-to-uridine RNA editing / S. Cho ... [et al.] -- RNA editing in plant mitochondria: Assays and biochemical approaches / M. Takenaka ... [et al.] -- Assay of editing of exogenous RNAs in chloroplast extracts of Arabidopsis, maize, pea, and tobacco / M.L. Hayes ... [et al.] -- In organello gene expression and RNA editing studies by electroporation-mediated transformation of isolated plant mitochondria / J. Farre ... [et al.] -- Transformation of the plastid genome to study RNA editing / K.A. Lutz ... [et al.].
504			_aIncludes bibliographical references and indexes.
588			_aDescription based on print version record.
520			_aRNA processing plays a critical role in realizing the full potential of a given genome. One means of achieving protein diversity is through RNA editing. A diverse array of editing events has been characterized, affecting gene expression in organisms from viruses and single cell parasites to humans and plants. The variety of editing mechanisms has required the development of many different experimental approaches, many of which are likely to be broadly applicable, particularly given the interplay between editing and other cellular processes, including transcription, splicing, and RNA silencing. This volume not only covers most of the principal methods employed in the field, but also offers innovative solutions to the significant challenges posed by these experimental systems. * Presents newly developed methods * Covers topics ranging from biochemistry to bioinformatics * Includes innovative solutions to potential problems.
650		0	_aRNA editing.
650		7	_aSCIENCE _xLife Sciences _xMolecular Biology. _2bisacsh
650		7	_aRNA editing. _2fast _0(OCoLC)fst01086255
650		2	_aRNA Editing.
655		4	_aElectronic books.
700	1		_aGott, Jonatha M.
776	0	8	_iPrint version: _tRNA editing. _dSan Diego, Calif. : Academic Press/Elsevier, c2007 _z9780123739223 _z0123739225 _w(OCoLC)154660891
830		0	_aMethods in enzymology ; _vv. 424. _x0076-6879
856	4	0	_3ScienceDirect _uhttp://www.sciencedirect.com/science/book/9780123739223
856	4	0	_3ScienceDirect _uhttp://www.sciencedirect.com/science/bookseries/00766879/424
938			_aYBP Library Services _bYANK _n2636975
938			_aBaker and Taylor _bBTCP _nBK0007491354
938			_aEBSCOhost _bEBSC _n205304
942			_cEB
994			_aC0 _bTEF
999			_c21599 _d21599