| 000 | 03321cam a2200517Ia 4500 | ||
|---|---|---|---|
| 001 | ocn828715991 | ||
| 003 | OCoLC | ||
| 005 | 20141103172220.0 | ||
| 006 | m o d | ||
| 007 | cr cnu---unuuu | ||
| 008 | 130218s2013 caua ob 001 0 eng | ||
| 040 |
_aAU@ _beng _cAU@ _dOCLCO _dE7B _dOCLCQ _dCUS _dIDEBK _dUIU _dUAT _dCDX _dOPELS _dN$T _dOCLCF _dKUK |
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| 019 | _a829742131 | ||
| 020 | _a9780123946294 (electronic bk.) | ||
| 020 | _a0123946298 (electronic bk.) | ||
| 020 | _z9780123942920 (hbk.) | ||
| 020 | _z0123942926 (hbk.) | ||
| 029 | 0 |
_aAU@ _b000050544849 |
|
| 035 |
_a(OCoLC)828715991 _z(OCoLC)829742131 |
||
| 050 | 4 |
_aQP601 _b.C733 v.523 |
|
| 072 | 7 |
_aSCI _x010000 _2bisacsh |
|
| 082 | 0 | 4 |
_a660.6/3 _223 |
| 049 | _aTEFA | ||
| 245 | 0 | 0 |
_aMethods in protein design _h[electronic resource] / _cedited by Amy E. Keating. |
| 260 |
_aSan Diego, Calif. : _bAcademic, _c2013. |
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| 300 |
_a1 online resource (xviii, 464 p.) : _bill. |
||
| 490 | 1 |
_aMethods in enzymology, _x0076-6879 ; _v523 |
|
| 504 | _aIncludes bibliographical references and indexes. | ||
| 505 | 0 | _aComputational design of novel protein binders and experimental affinity maturation -- Mining tertiary structural motifs for assessment of designability -- Computational methods for controlling binding specificity -- Flexible backbone sampling methods to model and design protein alternative conformations -- Osprey: protein design with ensembles, flexibility, and provable algorithms -- Scientific benchmarks for guiding macromolecular energy function improvement -- Molecular dynamics simulations for the ranking, evaluation, and refinement of computationally designed proteins -- Multistate protein design using CLEVER and CLASSY -- Using analyses of amino acid coevolution to understand protein structure and function -- Evolution-based design of proteins -- Protein engineering and stabilization from sequence statistics: variation and covariation analysis -- Enzyme engineering by targeted libraries -- Generation of high-performance binding proteins for pepetide motifs by affinity clamping -- Engineering fibronectin-based binding proteins by yeast surface display -- Engineering and analysis of peptide-recognition domain specificities by phage display and deep sequencing -- Efficient sampling of SCHEMA chimera families to identify useful sequence elements -- Protein switch engineering by domain insertion -- Design of chimeric proteins by combination of subdomain-sized fragments -- [alpha]-helix mimicry with [alpha/beta]-peptides. | |
| 588 | _aDescription based on print version record. | ||
| 650 | 0 | _aProtein engineering. | |
| 650 | 4 | _aEjournals -- UML. | |
| 650 | 7 |
_aSCIENCE / Biotechnology _2bisacsh |
|
| 650 | 7 |
_aProtein engineering. _2fast _0(OCoLC)fst01079685 |
|
| 655 | 4 | _aElectronic books. | |
| 700 | 1 | _aKeating, Amy E. | |
| 830 | 0 |
_aMethods in enzymology ; _vv. 523. _x0076-6879 |
|
| 856 | 4 | 0 |
_3Science Direct _uhttp://www.sciencedirect.com/science/book/9780123942920 |
| 856 | 4 | 0 |
_3ScienceDirect _uhttp://www.sciencedirect.com/science/bookseries/00766879/523 |
| 938 |
_aIngram Digital eBook Collection _bIDEB _ncis24763797 |
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| 938 |
_aebrary _bEBRY _nebr10658873 |
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| 938 |
_aCoutts Information Services _bCOUT _n24763797 |
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| 938 |
_aEBSCOhost _bEBSC _n541240 |
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| 942 | _cEB | ||
| 994 |
_aC0 _bTEF |
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| 999 |
_c21452 _d21452 |
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