000			03822cam a2200553Ia 4500
001			ocn127111637
003			OCoLC
005			20141103172216.0
006			m o d
007			cr cnu---unuuu
008			070515s2006 ne a ob 001 0 eng d
040			_aN$T _beng _cN$T _dOCLCQ _dIDEBK _dOCLCQ _dCOF _dOCLCQ _dOPELS _dOCLCQ _dOPELS _dOCLCF _dKUK
020			_a9780080464664 (electronic bk.)
020			_a0080464661 (electronic bk.)
020			_a0121828166 (electronic bk.)
020			_a9780121828165 (electronic bk.)
020			_z9780121828165 (v. 411)
035			_a(OCoLC)127111637
050		4	_aQP601 _b.C733eb vol. 411
072		7	_aSCI _x007000 _2bisacsh
082	0	4	_a572/.7 _222
049			_aTEFA
245	0	0	_aDNA microarrays. _npt. B, _pDatabases and statistics _h[electronic resource] / _cedited by Alan Kimmel & Brian Oliver.
246	3	0	_aDatabases and statistics
260			_aAmsterdam ; _aSan Diego : _bElsevier/Academic Press, _cc2006.
300			_a1 online resource (xxxvi, 469) : _bill.
490	1		_aMethods in enzymology ; _vv. 411
504			_aIncludes bibliographical references and indexes.
588			_aDescription based on print version record.
520			_aModern DNA microarray technologies have evolved over the past 25 years to the point where it is now possible to take many million measurements from a single experiment. These two volumes, Parts A & B in the Methods in Enzymology series provide methods that will shepard any molecular biologist through the process of planning, performing, and publishing microarray results. Part A starts with an overview of a number of microarray platforms, both commercial and academically produced and includes wet bench protocols for performing traditional expression analysis and derivative techniques such as detection of transcription factor occupancy and chromatin status. Wet-bench protocols and troubleshooting techniques continue into Part B. These techniques are well rooted in traditional molecular biology and while they require traditional care, a researcher that can reproducibly generate beautiful Northern or Southern blots should have no difficulty generating beautiful array hybridizations. Data management is a more recent problem for most biologists. The bulk of Part B provides a range of techniques for data handling. This includes critical issues, from normalization within and between arrays, to uploading your results to the public repositories for array data, and how to integrate data from multiple sources. There are chapters in Part B for both the debutant and the expert bioinformatician. Provides an overview of platforms Includes experimental design and wet bench protocols. Presents statistical and data analysis methods, array databases, data visualization and meta analysis.
650		0	_aDNA microarrays.
650		0	_aDNA.
650		2	_aOligonucleotide Array Sequence Analysis _xmethods.
650		2	_aOligonucleotide Array Sequence Analysis _xstatistics & numerical data.
650		2	_aGene Expression Profiling _xmethods.
650		7	_aSCIENCE _xLife Sciences _xBiochemistry. _2bisacsh
650		7	_aDNA. _2fast _0(OCoLC)fst00886555
650		7	_aDNA microarrays. _2fast _0(OCoLC)fst00886592
655		4	_aElectronic books.
700	1		_aKimmel, Alan R.
700	1		_aOliver, Brian, _d1959-
776	0	8	_iPrint version: _tDNA microarrays. pt. B, Databases and statistics. _dAmsterdam ; San Diego : Elsevier/Academic Press, c2006 _z0121828166 _z9780121828165 _w(OCoLC)71503200
830		0	_aMethods in enzymology ; _vv. 411.
856	4	0	_3ScienceDirect _uhttp://www.sciencedirect.com/science/book/9780121828165
856	4	0	_3ScienceDirect _uhttp://www.sciencedirect.com/science/bookseries/00766879/411
938			_aEBSCOhost _bEBSC _n173542
942			_cEB
994			_aC0 _bTEF
999			_c21280 _d21280