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008 070423s2007 ne af ob 001 0 eng d
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019 _a163616130
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020 _a9780080471013 (electronic bk.)
020 _a0080471013 (electronic bk.)
020 _a0120066963 (electronic bk.)
020 _a9780120066964 (electronic bk.)
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035 _a(OCoLC)123420906
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082 0 4 _a616.99/406
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084 _a44.81
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049 _aTEFA
245 0 0 _aGenomics in cancer drug discovery and development
_h[electronic resource] /
_cedited by Garret M. Hampton, Karol Sikora.
260 _aAmsterdam, NE ;
_aBoston, MA :
_bElsevier,
_cc2007.
300 _a1 online resource (xix, 409 p., [16] p. of col. plates) :
_bill.
336 _atekst
_btxt
_2rdacontent/dut
337 _acomputer
_bc
_2rdamedia/dut
338 _aonline bron
_bcr
_2rdacarrier/dut
490 1 _aAdvances in cancer research,
_x0065-230X ;
_vv. 96
504 _aIncludes bibliographical references and index.
505 0 _aContributors to Volume 96 -- Introduction / Garret M. Hampton, Karol Sikora -- Biomarker Discovery in Epithelial Ovarian Cancer by Genomic Approaches / Samuel C. Mok, Kevin M. Elias, Kwong-Kwok Wong, Kae Ho, Tomas Bonome, and Michael J. Birrer -- Mass Spectrometry: Uncovering the Cancer Proteome for Diagnostics / Da-Elene van der Merwe, Katerina Oikonomopoulou, John Marshall, and Eleftherios P. Diamandis -- Microarrays to Identify New Therapeutic Strategies for Cancer / Christopher Sears and Scott A. Armstrong -- The Application of siRNA Technology to Cancer Biology Discovery / Uta Fuchs and Arndt Borkhardt -- Ribozyme Technology for Cancer Gene Target Identification and Validation / Qi-Xiang Li, Philip Tan, Ning Ke, and Flossie Wong-Staal -- Cancer Cell-Based Genomic and Small Molecule Screens / Jeremy S. Caldwell -- Tumor Antigens as Surrogate Markers and Targets for Therapy and Vaccines / Angus Dalgleish and Hardev Pandha -- Practices and Pitfalls of Mouse Cancer Models in Drug Discovery / Andrew L. Kung -- Pharmacodynamic Biomarkers for Molecular Cancer Therapeutics / Debashis Sarker and Paul Workman -- Biomarker Assay Translation from Discovery to Clinical Studies in Cancer Drug Development: Quantification of Emerging Protein Biomarkers / Jean W. Lee, Daniel Figeys, and Julian Vasilescu -- Molecular Optical Imaging of Therapeutic Targets of Cancer / Kostantin Sokolov, Dawn Nida, Michael Descour, Alicia Lacy, Matthew Levy, Brad Hall, Su Dharmawardhane, Andrew Ellington, Brian Korgel, and Rebecca Richards-Kortum -- Personalized Medicine for Cancer: From Molecular Signature to Therapeutic Choice / Karol Sikora -- Cancer Drug Approval in the United States, Europe, and Japan / R.A.V. Milsted -- Index.
588 _aDescription based on print version record.
520 _aThe Advances in Cancer Research series provides invaluable information on the exciting and fast-moving field of cancer research. This volume stands as the first ever thematic volume in the series, focusing on the topic of genomics in cancer drug development. The chapters included in this book represent the cutting-edge information in the field and span such topics as Mass Spectrometry: Uncovering the Cancer Proteome for Diagnostics; Biomarker Discovery in Epithelial Ovarian Cancer by Genomic Approaches; The Application of siRNA Technology to Cancer Biology Discovery; Ribozyme Technology for Cancer Gene Target Identification and Validation; Cancer Cell-Based Genomic and Small Molecule Screens; Tumour Antigens as Surrogate Markers and Targets for Therapy and Vaccines; Practices and Pitfalls of Mouse Cancer Models in Drug Discovery; Biomarker Assay Translation from Discovery to Clinical Studies in Cancer Drug Development - Quantification of Emerging Protein Biomarkers; Molecular Optical Imaging of Therapeutic Targets of Cancer; Cancer Drug Approval in the United States, Europe and Japan.
650 0 _aCancer
_xTreatment.
650 0 _aCancer
_xResearch.
650 0 _aCancer
_xGenetic aspects.
650 0 _aTumors
_xGenetic aspects.
650 0 _aGenomics.
650 2 _aGenomics
_xmethods.
650 2 _aNeoplasms
_xtherapy.
650 7 _aMEDICAL
_xOncology.
_2bisacsh
650 7 _aHEALTH & FITNESS
_xDiseases
_xCancer.
_2bisacsh
650 4 _aElectronic books.
650 1 7 _aKanker.
_2gtt
650 7 _aCancer
_xGenetic aspects.
_2fast
_0(OCoLC)fst00845368
650 7 _aCancer
_xResearch.
_2fast
_0(OCoLC)fst00845497
650 7 _aCancer
_xTreatment.
_2fast
_0(OCoLC)fst00845538
650 7 _aGenomics.
_2fast
_0(OCoLC)fst00940228
650 7 _aTumors
_xGenetic aspects.
_2fast
_0(OCoLC)fst01158768
655 4 _aElectronic books.
700 1 _aHampton, Garret M.
700 1 _aSikora, Karol.
776 0 8 _iPrint version:
_tGenomics in cancer drug discovery and development.
_dAmsterdam, NE ; Boston, MA : Elsevier, c2007
_z0120066963
_z9780120066964
_w(OCoLC)80548348
830 0 _aAdvances in cancer research ;
_vv. 96.
_x0065-230X
856 4 0 _3ScienceDirect
_uhttp://www.sciencedirect.com/science/book/9780120066964
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