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Natural product biosynthesis by microorganisms and plants. Part B [electronic resource] / edited by David A. Hopwood.

Contributor(s): Hopwood, D. AMaterial type: TextTextSeries: Methods in enzymology ; v. 516. | Natural product biosynthesis by microorganisms and plants ; pt. B.Publication details: San Diego, Calif. : Elsevier, 2012. Description: 1 online resource (lvi, 393 p., [12] p. of col. plates :) ill. (some col.)ISBN: 9780123946287 (electronic bk.); 012394628X (electronic bk.)Subject(s): Microbiological synthesis | Plant products -- Synthesis | Biosynthesis | Enzymes | SCIENCE / Life Sciences / Biochemistry | Biosynthesis | Enzymes | Microbiological synthesis | Plant products -- Synthesis | Chemistry Techniques, Synthetic -- methods | Peptide Biosynthesis, Nucleic Acid-Independent | Biosynthetic Pathways -- Laboratory Manuals | Plants -- enzymology -- Laboratory Manuals | Bacteria -- enzymology -- Laboratory Manuals | Fungi -- enzymology -- Laboratory ManualsGenre/Form: Electronic books.DDC classification: 572.45 LOC classification: QR88.3 | .N38 2012ebOnline resources: ScienceDirect | ScienceDirect
Contents:
In vivo production of thiopeptide variants / Feifei Zhang and Wendy L. Kelly -- Microviridin biosynthesis / Thomas K. Hemscheidt -- Cyclotide isolation and characterization / David J. Craik, Sonia Troeira Henriques, Joshua S. Mylne, and Conan K. Wang -- Ribosomally encoded cyclic peptide toxins from mushrooms / Jonathan D. Walton, Hong Luo, and Heather Hallen-Adams -- The Pictet-Spengler mechanism involved in the biosynthesis of tetrahydroisoquinoline antitumor antibiotics: a novel function for a nonribosomal peptide synthetase / Kento Koketsu ... [et al.] -- Discovery and biosynthesis of phosphonate and phosphinate natural products / Spencer C. Peck, Jiangtao Gao, and Wilfred A van der Donk -- RlmN and AtsB as models for the overproduction and characterization of radical SAM proteins / Nicholas D. Lanz ... [et al.] -- Fe(II)-dependent, uridine-5'-monophosphate [alpha]-ketoglutarate dioxygenases in the synthesis of 5'-modified nucleosides / Zhaoyong Yang, Jason Unrine, Koichi Nonaka, and Steven G. Van Lanen --
Tailoring reactions catalyzed by heme-dependent enzymes: spectroscopic characterization of the L-tryptophan-nitrating cytochrome P450 TxtE / Sarah M. Barry and Gregory L. Challis -- Oxidative tailoring reactions: catalyzed by nonheme iron-dependent enzymes: streptorubin B biosynthesis as an example / Paulina K. Sydor and Gregory L. Challis -- The rare fluorinated natural products and biotechnological prospects for fluorine enzymology / K.K. Jason Chan and David O'Hagan -- Enzymatic chlorination and bromination / Karl-Heinz van P�ee -- Prenyltransferases of the dimethylallyltryptophan synthase superfamily / Xia Yu and Shu-Ming Li -- Serine carboxypeptidase-like acyltransferases from plants / Sam T. Mugford and Carsten Milkowski -- 4-methylideneimidazole-5-one-containing aminomutases in enediyne biosynthesis / Jeremy R. Lohman and Ben Shen -- Tailoring enzymes acting on carrier protein-tethered substrates in natural product biosynthesis / Shuangjun Lin, Tingting Huang, and Ben Shen -- High-throughput colorimetric assays for nucleotide sugar formation and glycosyl transfer / Richard W. Gantt and Jon S. Thorson.
Summary: This new volume of Methods in Enzymology continues the legacy of this premier serial by containing quality chapters authored by leaders in the field. The second of 3 volumes covering Natural product biosynthesis by microorganisms and plants. This new volume continues the legacy of this premier serialContains quality chapters authored by leaders in the field The second of 3 volumes it has chapters on such topics as biological chlorination, bromination and iodination, and phylogenetic approaches to natural product structure prediction.
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Includes bibliographical references and index.

In vivo production of thiopeptide variants / Feifei Zhang and Wendy L. Kelly -- Microviridin biosynthesis / Thomas K. Hemscheidt -- Cyclotide isolation and characterization / David J. Craik, Sonia Troeira Henriques, Joshua S. Mylne, and Conan K. Wang -- Ribosomally encoded cyclic peptide toxins from mushrooms / Jonathan D. Walton, Hong Luo, and Heather Hallen-Adams -- The Pictet-Spengler mechanism involved in the biosynthesis of tetrahydroisoquinoline antitumor antibiotics: a novel function for a nonribosomal peptide synthetase / Kento Koketsu ... [et al.] -- Discovery and biosynthesis of phosphonate and phosphinate natural products / Spencer C. Peck, Jiangtao Gao, and Wilfred A van der Donk -- RlmN and AtsB as models for the overproduction and characterization of radical SAM proteins / Nicholas D. Lanz ... [et al.] -- Fe(II)-dependent, uridine-5'-monophosphate [alpha]-ketoglutarate dioxygenases in the synthesis of 5'-modified nucleosides / Zhaoyong Yang, Jason Unrine, Koichi Nonaka, and Steven G. Van Lanen --

Tailoring reactions catalyzed by heme-dependent enzymes: spectroscopic characterization of the L-tryptophan-nitrating cytochrome P450 TxtE / Sarah M. Barry and Gregory L. Challis -- Oxidative tailoring reactions: catalyzed by nonheme iron-dependent enzymes: streptorubin B biosynthesis as an example / Paulina K. Sydor and Gregory L. Challis -- The rare fluorinated natural products and biotechnological prospects for fluorine enzymology / K.K. Jason Chan and David O'Hagan -- Enzymatic chlorination and bromination / Karl-Heinz van P�ee -- Prenyltransferases of the dimethylallyltryptophan synthase superfamily / Xia Yu and Shu-Ming Li -- Serine carboxypeptidase-like acyltransferases from plants / Sam T. Mugford and Carsten Milkowski -- 4-methylideneimidazole-5-one-containing aminomutases in enediyne biosynthesis / Jeremy R. Lohman and Ben Shen -- Tailoring enzymes acting on carrier protein-tethered substrates in natural product biosynthesis / Shuangjun Lin, Tingting Huang, and Ben Shen -- High-throughput colorimetric assays for nucleotide sugar formation and glycosyl transfer / Richard W. Gantt and Jon S. Thorson.

Description based on print version record.

This new volume of Methods in Enzymology continues the legacy of this premier serial by containing quality chapters authored by leaders in the field. The second of 3 volumes covering Natural product biosynthesis by microorganisms and plants. This new volume continues the legacy of this premier serialContains quality chapters authored by leaders in the field The second of 3 volumes it has chapters on such topics as biological chlorination, bromination and iodination, and phylogenetic approaches to natural product structure prediction.

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