Correlative light and electron microscopy [electronic resource] / edited by Thomas M�uller-Reichert [and] Paul Verkade.
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TextSeries: Methods in cell biology ; v. 111.Publication details: Amsterdam, Netherlands ; Boston, Mass. : Elsevier / Academic Press c2012. Description: 1 online resource ( xix, 404 p., [40] p. of plates) : ill. (some col.)ISBN: 9780123914385 (electronic bk.); 0123914388 (electronic bk.)Subject(s): Electron microscopy -- Technique | Microscopy, Electron | Light | SCIENCE / Electron Microscopes & Microscopy | Electron microscopy -- TechniqueGenre/Form: Electronic books.DDC classification: 502.8/25 LOC classification: QH212.E4 | C677 2012ebOnline resources: ScienceDirect Summary: The combination of electron microscopy with transmitted light microscopy (termed correlative light and electron microscopy; CLEM has been employed for decades to generate molecular identification that can be visualized by a dark, electron-dense precipitate. This new volume of Methods in Cell Biology covers many areas of CLEM including a brief history and overview on CLEM methods, imaging of intermediate stages of meiotic spindle assembly in C. elegans embryos using CLEM, and capturing endocytic segregation events with HPF-CLEM. Covers many areas of CLEM by the best international scientists in the field. Includes a brief history and overview on CLEM methods.
Includes bibliographical references and index.
The combination of electron microscopy with transmitted light microscopy (termed correlative light and electron microscopy; CLEM has been employed for decades to generate molecular identification that can be visualized by a dark, electron-dense precipitate. This new volume of Methods in Cell Biology covers many areas of CLEM including a brief history and overview on CLEM methods, imaging of intermediate stages of meiotic spindle assembly in C. elegans embryos using CLEM, and capturing endocytic segregation events with HPF-CLEM. Covers many areas of CLEM by the best international scientists in the field. Includes a brief history and overview on CLEM methods.
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