Non-natural amino acids [electronic resource] / edited by Tom W. Muir, John N. Abelson.
Material type: TextSeries: Methods in enzymology ; v. 462.Publication details: Amsterdam ; Boston : San Diego, CA : Elsevier ; Academic Press, 2009. Edition: 1st edDescription: 1 online resource (xliii, 264 pages) : illustrationsContent type: text Media type: computer Carrier type: online resourceISBN: 9780080921631 (electronic bk.); 0080921639 (electronic bk.); 9780123743107 (electronic bk.); 0123743109 (electronic bk.)Subject(s): Amino acids | Proteins | SCIENCE -- Life Sciences -- Biochemistry | Amino acids | ProteinsGenre/Form: Electronic books.Additional physical formats: Print version:: Non-natural amino acids.DDC classification: 572/.65 LOC classification: QP561 | .N66 2009ebOnline resources: ScienceDirect | ScienceDirectIncludes bibliographical references and indexes.
Front Cover; Methods in Enzymology; Copyright Page; Contents; Contributors; Preface; Methods in Enzymology; Chapter 1: Protein Phosphorylation by Semisynthesis: From Paper to Practice; Chapter 2: Protein Engineering with the Traceless Staudinger Ligation; Chapter 3: Replacement of Y730 and Y731 in the alpha2 Subunit of Escherichia coli Ribonucleotide Reductase with 3-Aminotyrosine using and Evolved Suppressor tRNA/tRNA- Synthetase Pair; Chapter 4: Semisynthesis of Proteins Using Split Inteins; Chapter 5: Expressed Protein Ligation for Metalloprotein Design and Engineering.
By combining the tools of organic chemistry with those of physical biochemistry and cell biology, this title provides fundamental insights into how proteins work within the context of complex biological systems of biomedical interest.
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