TY  - BOOK
AU  - Le, Anne
TI  - Heterogeneity of cancer metabolism
T2  - Advances in experimental medicine and biology ; 
SN  - 9783319777351
U1  - 616-006 
PY  - 2018///
CY  - Cham : 
PB  - Springer, 
KW  - Biomedicine
KW  - Cancer
KW  - Treatment
KW  - Cancer cells
KW  - Metabolism
KW  - Molecular aspects
KW  - Cancer research
KW  - Epigenetics and oncometabolites
KW  - Glutamine metabolism
KW  - Medical
KW  - Oncology
N1  - Includes bibliographical references and index
N2  - Genetic alterations in cancer, in addition to being the fundamental drivers of tumorigenesis, can give rise to a variety of metabolic adaptations that allow cancer cells to survive and proliferate in diverse tumor microenvironments. This metabolic flexibility is different from normal cellular metabolic processes and leads to heterogeneity in cancer metabolism within the same cancer type or even within the same tumor.

In this book, we delve into the complexity and diversity of cancer metabolism, and highlight how understanding the heterogeneity of cancer metabolism is fundamental to the development of effective metabolism-based therapeutic strategies. Deciphering how cancer cells utilize various nutrient resources will enable clinicians and researchers to pair specific chemotherapeutic agents with patients who are most likely to respond with positive outcomes, allowing for more cost-effective and personalized cancer therapeutic strategies
UR  - https://link.springer.com/content/pdf/bfm:978-3-319-77736-8/1
UR  - https://www.goodreads.com/book/show/38512895-the-heterogeneity-of-cancer-metabolism#CommunityReviews
UR  - https://link.springer.com/book/10.1007/978-3-030-65768-0
ER  -