TY  - BOOK
AU  - Keating,Amy E.
TI  - Methods in protein design
T2  - Methods in enzymology,
SN  - 9780123946294 (electronic bk.)
AV  - QP601 .C733 v.523
U1  - 660.6/3 23
PY  - 2013///
CY  - San Diego, Calif.
PB  - Academic
KW  - Protein engineering
KW  - Ejournals -- UML
KW  - SCIENCE / Biotechnology
KW  - bisacsh
KW  - fast
KW  - Electronic books
N1  - Includes bibliographical references and indexes; Computational design of novel protein binders and experimental affinity maturation -- Mining tertiary structural motifs for assessment of designability -- Computational methods for controlling binding specificity -- Flexible backbone sampling methods to model and design protein alternative conformations -- Osprey: protein design with ensembles, flexibility, and provable algorithms -- Scientific benchmarks for guiding macromolecular energy function improvement -- Molecular dynamics simulations for the ranking, evaluation, and refinement of computationally designed proteins -- Multistate protein design using CLEVER and CLASSY -- Using analyses of amino acid coevolution to understand protein structure and function -- Evolution-based design of proteins -- Protein engineering and stabilization from sequence statistics: variation and covariation analysis -- Enzyme engineering by targeted libraries -- Generation of high-performance binding proteins for pepetide motifs by affinity clamping -- Engineering fibronectin-based binding proteins by yeast surface display -- Engineering and analysis of peptide-recognition domain specificities by phage display and deep sequencing -- Efficient sampling of SCHEMA chimera families to identify useful sequence elements -- Protein switch engineering by domain insertion -- Design of chimeric proteins by combination of subdomain-sized fragments -- [alpha]-helix mimicry with [alpha/beta]-peptides
UR  - http://www.sciencedirect.com/science/book/9780123942920
UR  - http://www.sciencedirect.com/science/bookseries/00766879/523
ER  -