TY  - BOOK
AU  - Carter,Charles W.
AU  - Sweet,Robert M.
TI  - Macromolecular crystallography
T2  - Methods in enzymology
SN  - 0080497098 (electronic bk.)
AV  - QP601 
U1  - 548.3 21
PY  - 2003///
CY  - Amsterdam, Oxford
PB  - Elsevier Academic Press
KW  - X-ray crystallography
KW  - Enzymes
KW  - Analysis
KW  - Proteins
KW  - fast
KW  - Electronic books
N1  - Includes bibliographical references and index; Cover -- Table of Contents -- Contributor to Volume 368 -- Preface -- Volumes in Series -- Section I: Reminiscences on Methods -- Chapter 1. Transformations in Structural Biology: Personal View -- Chapter 2. Origins -- Chapter 3. Personal X-ray Reflections -- Section II: Crystals -- Chapter 4. Robotics for Automated Crystal Formation and Analysis -- Chapter 5. Use of Limited Proteolysis to Identify Protein Domains Suitable for Structural Analysis -- Chapter 6. Solvent Entropy Effects in the Formation of Protein Solid Phases -- Chapter 7. Controlling Biomolecular Crystallization by Understanding the Distinct Effects of PEGs and Salts on Solubility -- Chapter 8. Counter-diffusion Methods for Macromolecular Crystallization -- Chapter 9. Growth Sectors and Crystal Quality -- Chapter 10. Molecular Mechanisms of Defect Formation -- Chapter 11. Cryocooling of Macromolecular Crystals: Optimization Methods -- Chapter 12. The Well-Tempered Protein Crystal:Annealing Macromolecular Crystals -- Section III: Data -- Chapter 13. What Can I Have As a Source of X-Ray Synchrotron Radiation? A Primer for Potential Users -- Chapter 14. Protein Crystal Structure Analysis from High- Resolution X-Ray Powder-Diffraction Data -- Chapter 15. Macromolecular Crystal Quality -- Chapter 16. Protein Structures at Atomic Resolution -- Author Index -- Subject Index -- Color Plates Section -- Last Page
N2  - Accurate molecular structures are vital for rational drug design and for structure-based functional studies directed toward the development of effective therapeutic agents and drugs. Crystallography can reliably predict structure, both in terms of folding and atomic details of bonding. * Methodological methods in crystals * Methodological methods data analysis
UR  - http://www.sciencedirect.com/science/book/9780121822712
UR  - http://www.sciencedirect.com/science/bookseries/00766879/368
ER  -