TY  - BOOK
AU  - Conn,P.Michael
TI  - G protein coupled receptors
T2  - Methods in enzymology,
SN  - 9780124078659
AV  - QP552.G16 .G384 2013 
U1  - 572/.696 23
PY  - 2013///
CY  - San Diego, Calif.
PB  - Academic
KW  - Cell receptors
KW  - Structure-activity relationships
KW  - G proteins
KW  - Receptors
KW  - fast
KW  - Electronic books
N1  - Includes bibliographical references and indexes; The protein local optimization program and g-protein-coupled receptors:loop restoration and applications to homology modeling -- Modeling active GPCR conformations -- Molecular modeling of adenosine receptors -- Predicting g-protein-coupled receptors families using differet physiochemical properties and pseudo amino acid composition -- Computational design and experimental characterization of GPCR segment models -- G-protein-coupled receptor interaction with small GTPases -- Quantification of receptor tyrosine kinase activiation and transactivation by G-protein-coupled receptors using spatial intensity distribution analysis (SplDA) -- NMR modeling for detection of small molecule binding to RGS4 -- Group II activators of g-protein signaling: monitoring the interaction of G[alpha] with G-protein motif in the intact cell -- Homogenous time-resolved fluorescence assay to probe folded G protein-coupled receptors -- cAMP biosensors applied in molecular pharmacological studies of G protein-coupled receptors -- Rhodospin-lipid intereactions studied by NMR -- Biasing the parathyroid hormone receptor: relating in vitro ligand efficacy to in vivo biological activity -- Application of Monte Carlo-based receptor ensemble docking to virtual screening for GPCR ligands -- From heptahelical bundle to hits from the haystack: structure-based virtual screening for GPCR ligands -- Kinetics and dynamics in the G protein-coupled receptor signaling cascade -- Magic angle spinning nuclear magnetic resonance spectroscopy fo G protein-coupled receptors -- Posttranslation modification of G protein-coupled receptor in relationship to biased agonism -- Protein S-nitrosylation measurement
UR  - http://www.sciencedirect.com/science/book/9780124078659
UR  - http://www.sciencedirect.com/science/bookseries/00766879/522
ER  -