TY - BOOK AU - Galluzzi,Lorenzo AU - Kroemer,Guido TI - Cell-wide metabolic alterations associated with malignancy T2 - Methods in enzymology, SN - 9780128014837 (electronic bk.) AV - QP601 U1 - 574.1 PY - 2014/// CY - Burlington PB - Elsevier Science KW - Biochemistry KW - Cancer KW - Enzymes KW - Neoplasms KW - Metabolism KW - Biochemistry -- Analysis KW - Biochemistry -- Technique KW - Biotechnology -- Methodology KW - Cells -- Laboratory manuals KW - Enzymes -- Analysis KW - SCIENCE / Life Sciences / Biology KW - bisacsh KW - Electronic books N2 - This new volume of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers research methods providing a theoretical overview on metabolic alterations of cancer cells and a series of protocols that can be employed to study oncometabolism, in vitro, ex vivo and in vivo. Malignant cells exhibit metabolic changes when compared to their normal counterparts, owing to both genetic and epigenetic alterations. Although such a metabolic rewiring has recently been indicated as ""yet another"" general hallmark of canc UR - http://www.sciencedirect.com/science/bookseries/00766879/543 UR - http://www.sciencedirect.com/science/book/9780128013298 ER -