TY - BOOK AU - Rouleau,Guy AU - Gaspar,Claudia TI - Advances in genetics T2 - Advances in genetics SN - 9780123745279 (electronic bk.) AV - QH431.A1 A363 2008eb U1 - 571.6/4 23 PY - 2008/// CY - Amsterdam, Boston PB - Academic Press KW - Ion channels KW - Membrane disorders KW - fast KW - Electronic books N1 - Includes bibliographical references and index N2 - Ion channel dysfunction in humans leads to impairment of the excitable processes necessary for the normal function of several tissues, such as muscle and brain. It follows that an increasing number of human diseases have been associated with malfunctioning ion channels, many of which have a genetic component. This volume presents a broad and comprehensive overview of the inherited channelopathies in humans, including clinical, genetic and molecular aspects of these conditions, as well as novel genomic and modeling research approaches. Also included is a review of potential therapeutic approaches for each of these conditions UR - http://www.sciencedirect.com/science/book/9780123745279 ER -