Mitochondrial dysfunction in aging and diseases of aging
Material type:
TextPublication details: Switzerland : MDPI, 2019 Description: ix, 256pISBN: 9783039213276Subject(s): Adaptive immunity | Age-related diseases | Age-related macular degeneration | Ageing | Alzheimers disease | Inflammation | Cell danger response | Neurodegenerative diseaseDDC classification: 576.311.347 Online resources: Reviews Summary: This collection of review articles authored by international experts pulls together current information about the role of mitochondria in aging and diseases of aging. Mitochondria are vitally important cellular organelles and undergo their own aging process becoming less efficient in aged animals including humans. These changes have wide-ranging significance contributing to immune dysfunction (autoimmunity and immune deficiency), inflammation, delayed healing, skin and retinal damage, cancer and most of the degenerative diseases of aging. Mitochondrial aging predisposes to drug toxicity in the geriatric population and to many of the features of normal aging. The research detailed in this book summarizes current understanding of the role of mitochondria in the complex molecular changes of aging, moving on to specific diseases of aging. Mitochondrial dysfunction is an important target for development of treatments for aging and disease. The last article details how exercise is a treatment and combats many features of the aging process.
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NISER LIBRARY | 576.311.347 HAA-M (Browse shelf(Opens below)) | Available | 25565 |
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| 576.311.33 -RIB Ribosome : structure, function, antibiotics and cellular interactions | 576.311.33 -RIB Ribosome : structure, function, antibiotics and cellular interactions | 576.311.33 -RIB Ribosome : structure, function, antibiotics and cellular interactions | 576.311.347 HAA-M Mitochondrial dysfunction in aging and diseases of aging | 576.311.347 LEI-M Mitochondria: practical protocols | 576.314 BIS-T Interplay of human full-length tau and K18 fragment with neuronal and synaptic membrane mimic | 576.314 KUB-B Bacterial ION channels and their eukaryotic homologs |
This collection of review articles authored by international experts pulls together current information about the role of mitochondria in aging and diseases of aging. Mitochondria are vitally important cellular organelles and undergo their own aging process becoming less efficient in aged animals including humans. These changes have wide-ranging significance contributing to immune dysfunction (autoimmunity and immune deficiency), inflammation, delayed healing, skin and retinal damage, cancer and most of the degenerative diseases of aging. Mitochondrial aging predisposes to drug toxicity in the geriatric population and to many of the features of normal aging. The research detailed in this book summarizes current understanding of the role of mitochondria in the complex molecular changes of aging, moving on to specific diseases of aging. Mitochondrial dysfunction is an important target for development of treatments for aging and disease. The last article details how exercise is a treatment and combats many features of the aging process.
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