Heterogeneity of cancer metabolism
Material type:
TextSeries: Advances in experimental medicine and biology ; volume 1063Publication details: Cham : Springer, 2018 Description: xv, 183pISBN: 9783319777351Subject(s): Biomedicine | Cancer -- Treatment | Cancer cells -- Metabolism | Cancer cells -- Molecular aspects | Cancer research | Epigenetics and oncometabolites | Glutamine metabolism | Medical -- OncologyDDC classification: 616-006 Online resources: Table of contents | Reviews | Second edition Summary: Genetic alterations in cancer, in addition to being the fundamental drivers of tumorigenesis, can give rise to a variety of metabolic adaptations that allow cancer cells to survive and proliferate in diverse tumor microenvironments. This metabolic flexibility is different from normal cellular metabolic processes and leads to heterogeneity in cancer metabolism within the same cancer type or even within the same tumor.
In this book, we delve into the complexity and diversity of cancer metabolism, and highlight how understanding the heterogeneity of cancer metabolism is fundamental to the development of effective metabolism-based therapeutic strategies. Deciphering how cancer cells utilize various nutrient resources will enable clinicians and researchers to pair specific chemotherapeutic agents with patients who are most likely to respond with positive outcomes, allowing for more cost-effective and personalized cancer therapeutic strategies.
| Item type | Current library | Call number | Status | Date due | Barcode |
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NISER LIBRARY | 616-006 LE-H (Browse shelf(Opens below)) | Available | 25332 |
Includes bibliographical references and index
Genetic alterations in cancer, in addition to being the fundamental drivers of tumorigenesis, can give rise to a variety of metabolic adaptations that allow cancer cells to survive and proliferate in diverse tumor microenvironments. This metabolic flexibility is different from normal cellular metabolic processes and leads to heterogeneity in cancer metabolism within the same cancer type or even within the same tumor.
In this book, we delve into the complexity and diversity of cancer metabolism, and highlight how understanding the heterogeneity of cancer metabolism is fundamental to the development of effective metabolism-based therapeutic strategies. Deciphering how cancer cells utilize various nutrient resources will enable clinicians and researchers to pair specific chemotherapeutic agents with patients who are most likely to respond with positive outcomes, allowing for more cost-effective and personalized cancer therapeutic strategies.
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