Epigenetic mechanisms in cancer

Contributor(s): Saldanha, Sabita [ed.]Material type: Text

TextSeries: Translational epigenetics series ; volume 3Publication details: London : Academic Press, 2018 Description: xii, 380 pages : illustrations (chiefly color)ISBN: 9780128095522Subject(s): Cancer -- Genetic aspects | Epigenesis, GeneticDDC classification: 616-006 Online resources: Reviews Summary: Epigenetic Mechanisms in Cancer provides a comprehensive analysis of epigenetic signatures that govern disease development, progression and metastasis. Epigenetic signatures dictating tumor etiologies present an opportunity for biomarker identification which has broad potential for improving diagnosis, prognosis, prediction, and risk assessment. This volumes offers a unique evaluation of signature differences in childhood, sex-specific and race-specific cancers, and in doing so broadly illuminates the scope of epigenetic biomarkers in clinical environments. Chapters detail the major epigenetic process in humans consisting of DNA methylation, histone modifications and microRNAs (miRNAs) involved in the initiation, progression and metastasis of tumors. Also delineated are recent technologies such as next generation sequencing that are used to identify epigenetic profiles (primarily methylation analysis) in samples (normal, benign and cancerous) and which are highly important to the analysis of epigenetic outcomes.

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Item type	Current library	Call number	Status	Date due	Barcode
Book	NISER LIBRARY	616-006 SAL-E (Browse shelf(Opens below))	Available		25330

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Previous	616.006 PRE-C Cancer immunotherapy: immune suppression and tumor growth	616-006 RAT-I Identification of FRG1 mutations in breast cancer and its functional implications	616-006 SAH-I Investigation of potential anticancer compounds in drosophila brain tumor models	616-006 SAL-E Epigenetic mechanisms in cancer	616-006 SHU-E Elucidating the role of FRG1 in regulating DNA damage and repair via HPF1 in breast tumorigenesis	616.006.6 DAN-M MYC and the pathway to cancer: a subject collection from cold spring harbor perspectives in medicine	616-006.6 HAS-U Understanding the role of EEF1A2 in Tumor Angiogenesis and Progression	Next

Includes bibliographical references at the end of each chapters and index.

Epigenetic Mechanisms in Cancer provides a comprehensive analysis of epigenetic signatures that govern disease development, progression and metastasis. Epigenetic signatures dictating tumor etiologies present an opportunity for biomarker identification which has broad potential for improving diagnosis, prognosis, prediction, and risk assessment. This volumes offers a unique evaluation of signature differences in childhood, sex-specific and race-specific cancers, and in doing so broadly illuminates the scope of epigenetic biomarkers in clinical environments. Chapters detail the major epigenetic process in humans consisting of DNA methylation, histone modifications and microRNAs (miRNAs) involved in the initiation, progression and metastasis of tumors. Also delineated are recent technologies such as next generation sequencing that are used to identify epigenetic profiles (primarily methylation analysis) in samples (normal, benign and cancerous) and which are highly important to the analysis of epigenetic outcomes.

Researchers, early clinicians and advanced students investigating cancer at the genetic level

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