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Cancer and noncoding RNAs

Contributor(s): Chakrabarti, Jayprokas [ed.] | Mitra, Sanga [ed.]Material type: TextTextSeries: Translational epigenetics series ; volume 1Publication details: London : Academic Press, 2018 Description: xxiii, 551 pages : illustrations (chiefly color) ; 25 cmISBN: 9780128110225Subject(s): Cancer -- Genetic aspects | Non-coding RNA | Carcinogenesis | RNA, Untranslated -- genetics | Epigenesis, Genetic | Neoplasms -- therapy | Genetic Therapy | Computational Biology -- methods | Cancer -- Genetic aspects | Non-coding RNADDC classification: 616-006 Online resources: Reviews Summary: Cancer and Noncoding RNAs offers an in-depth exploration of noncoding RNAs and their role in epigenetic regulation of complex human disease, most notably cancer. In addition to examining microRNAs, this volume provides a unique evaluation of more recently profiled noncoding RNAs now implicated in carcinogenesis, including lncRNAs, piRNAs, circRNAs, and tRNAs, identifying differences in function between these noncoding RNAs and how they interact with the rest of the epigenome. A broad range of chapters from experts in the field detail epigenetic regulation of various cancer types, along with recent next generation sequencing technologies, genome-wide association studies (GWAS) and bioinformatics approaches.
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Includes bibliographical referneces and index.

Cancer and Noncoding RNAs offers an in-depth exploration of noncoding RNAs and their role in epigenetic regulation of complex human disease, most notably cancer. In addition to examining microRNAs, this volume provides a unique evaluation of more recently profiled noncoding RNAs now implicated in carcinogenesis, including lncRNAs, piRNAs, circRNAs, and tRNAs, identifying differences in function between these noncoding RNAs and how they interact with the rest of the epigenome. A broad range of chapters from experts in the field detail epigenetic regulation of various cancer types, along with recent next generation sequencing technologies, genome-wide association studies (GWAS) and bioinformatics approaches.

This book will help researchers in genomic medicine and cancer biology better understand the role of noncoding RNAs in epigenetics, aiding in the development of useful biomarkers for diagnosis, prognosis and new RNA-based disease therapies.

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