RNA turnover in eukaryotes [electronic resource] : analysis of specialized and quality control RNA decay pathways / edited by Lynne E. Maquat, Megerditch Kiledjian.
Material type:
TextSeries: Methods in enzymology ; v. 449.Publication details: San Diego, Calif. : Academic, 2008. Description: 1 online resource (xliv, 417 p., [1] leaf of plates) : ill. (some col.)ISBN: 9780080923321 (electronic bk.); 0080923321 (electronic bk.); 9780123745842 (electronic bk.); 0123745845 (electronic bk.)Other title: Analysis of specialized and quality control RNA decay pathwaysSubject(s): Protista | RNA | SCIENCE -- Life Sciences -- Biology | SCIENCE -- Life Sciences -- Microbiology | Protista | RNA | RNA Precursors -- Laboratory Manuals | RNA Stability -- physiology -- Laboratory Manuals | Eukaryotic Cells -- metabolism -- Laboratory Manuals | RNA, Messenger -- metabolism -- Laboratory Manuals | mRNA Cleavage and Polyadenylation Factors -- Laboratory ManualsGenre/Form: Electronic books.Additional physical formats: Print version:: RNA turnover in eukaryotes; Print version:: RNA turnover in eukaryotes.DDC classification: 579 LOC classification: QP601 | .M49eb v. 449Online resources: ScienceDirect | ScienceDirect Summary: Specific complexes of protein and RNA carry out many essential biological functions, including RNA processing, RNA turnover, RNA folding, as well as the translation of genetic information from mRNA into protein sequences. Messenger RNA (mRNA) decay is now emerging as an important control point and a major contributor to gene expression. Continuing identification of the protein factors and cofactors, and mRNA instability elements responsible for mRNA decay allow researchers to build a comprehensive picture of the highly orchestrated processes involved in mRNA decay and its regulation. * Covers the nonsense-mediated mRNA decay (NMD) or mRNA surveillance pathway * Expert researchers introduce the most advanced technologies and techniques * Offers step-by-step lab instructions, including necessary equipment and reagents.
Includes bibliographical references and indexes.
Description based on print version record.
Specific complexes of protein and RNA carry out many essential biological functions, including RNA processing, RNA turnover, RNA folding, as well as the translation of genetic information from mRNA into protein sequences. Messenger RNA (mRNA) decay is now emerging as an important control point and a major contributor to gene expression. Continuing identification of the protein factors and cofactors, and mRNA instability elements responsible for mRNA decay allow researchers to build a comprehensive picture of the highly orchestrated processes involved in mRNA decay and its regulation. * Covers the nonsense-mediated mRNA decay (NMD) or mRNA surveillance pathway * Expert researchers introduce the most advanced technologies and techniques * Offers step-by-step lab instructions, including necessary equipment and reagents.
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