RNA-ligand interactions. Part A, Structural biology methods [electronic resource] / edited by Daniel W. Celander, John N. Abelson.
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TextSeries: Methods in enzymology ; v. 317.Publication details: San Diego, CA ; London : Academic Press, c2000. Description: 1 online resource (xxxiii, 549 p. [8] p. of col. plates) : illISBN: 0121822184 (electronic bk.); 9780121822187 (electronic bk.)Subject(s): Ligands (Biochemistry) | RNA | Ligands (Biochemistry) | RNA | Ligands | RNA -- physiologyGenre/Form: Electronic books.DDC classification: 612.0151 LOC classification: QP623.7 | .R537 2000ebOnline resources: ScienceDirect | ScienceDirect Summary: RNA-Ligand Interactions, Part A focuses on structural biology methods. Major topics covered include semisynthetic methodologies (RNA synthetic methods and derivatization of RNA); RNA structure determination (X-ray crystallography, NMR, EM); techniques for monitoring RNA conformation and dynamics (solution methods and electrophoretic and spectroscopic methods); and modeling tertiary structure: Part B, its companion Volume 318 of Methods in Enzymology, focuses on molecular biology methods. The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the Series contains much material still relevant today--truly an essential publication for researchers in all fields of life sciences.
Includes bibliographical references and indexes.
RNA-Ligand Interactions, Part A focuses on structural biology methods. Major topics covered include semisynthetic methodologies (RNA synthetic methods and derivatization of RNA); RNA structure determination (X-ray crystallography, NMR, EM); techniques for monitoring RNA conformation and dynamics (solution methods and electrophoretic and spectroscopic methods); and modeling tertiary structure: Part B, its companion Volume 318 of Methods in Enzymology, focuses on molecular biology methods. The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the Series contains much material still relevant today--truly an essential publication for researchers in all fields of life sciences.
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