Nitric oxide. Part B, Physiological and pathological processes [electronic resource] / edited by Lester Packer.

Contributor(s): Packer, LesterMaterial type: Text

TextSeries: Methods in enzymology ; v. 269.Publication details: San Diego : Academic Press, c1996. Description: 1 online resource (xxx, 528 p.) : illISBN: 0121821706 (electronic bk.); 9780121821708 (electronic bk.)Subject(s): Nitric oxide -- Physiological effect | Nitric oxide -- Metabolism | Nitric oxide -- Metabolism | Nitric oxide -- Physiological effectGenre/Form: Electronic books.Additional physical formats: Print version:: Nitric oxide. Part B, Physiological and pathological processes.DDC classification: 574.19258 LOC classification: QP601Online resources: ScienceDirect | ScienceDirect

Contents:

Effects of nitric oxide in cells and tissues. Biochemical reactivity of nitric oxide ; Tissue-specific effects of nitric oxide ; Nitric oxide and cellular signaling -- Pathological and clinical aspects of nitric oxide. Fingerprints of pathological action: nitrosylation, nitration, and nitrosation ; Interaction of nitric oxide with membranes, proteins, and nucleic acid ; Peroxynitrite ; Tissue and cellular cytotoxicity ; Clinical aspects.

Summary: Nitric oxide, recently named"Molecule of the Year"by the journal Science, impinges on a wide range of fields in biological research, particularly in the areas of biomedicine and cell and organismal biology, as well as in fundamental chemistry. This volume and its companion Volume 268 highlight methods used to research the physiology and toxicity of nitric oxide in cellular and organismal systems. It will be a valuable resource for the experienced researcher as well as for those newly entering the field. Key Features * Effects of nitric oxide in cells and tissues * Biochemical reactivity * Tissue-specific effects * Endothelial nitric oxide synthase expressions in heterologous systems * Cellular signaling * Pathological and clinical aspects of NO * Fingerprints of pathological action * Interaction with membranes, proteins, and nucleic acids * Peroxynitrite * Tissue and cellular cytotoxicity * Clinical aspects.

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Includes bibliographical references and index.

Description based on print version record.

Nitric oxide, recently named"Molecule of the Year"by the journal Science, impinges on a wide range of fields in biological research, particularly in the areas of biomedicine and cell and organismal biology, as well as in fundamental chemistry. This volume and its companion Volume 268 highlight methods used to research the physiology and toxicity of nitric oxide in cellular and organismal systems. It will be a valuable resource for the experienced researcher as well as for those newly entering the field. Key Features * Effects of nitric oxide in cells and tissues * Biochemical reactivity * Tissue-specific effects * Endothelial nitric oxide synthase expressions in heterologous systems * Cellular signaling * Pathological and clinical aspects of NO * Fingerprints of pathological action * Interaction with membranes, proteins, and nucleic acids * Peroxynitrite * Tissue and cellular cytotoxicity * Clinical aspects.

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