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Guide to techniques in mouse development [electronic resource] / edited by Paul M. Wassarman, Melvin L. DePamphilis.

Contributor(s): Wassarman, Paul M | DePamphilis, Melvin LMaterial type: TextTextSeries: Methods in enzymology ; v. 225.Publication details: San Diego : Academic Press, c1993. Description: 1 online resource (xxxviii, 1021 p.) : illISBN: 0121821269 (electronic bk.); 9780121821265 (electronic bk.)Subject(s): Molecular biology -- Technique | Mice as laboratory animals | Developmental biology | Mice -- genetics | Mice -- embryology | Genetic Techniques | Gene Expression | Souris -- D�eveloppement | Developmental biology | Mice as laboratory animals | Molecular biology -- Technique | Laboratory animalsGenre/Form: Electronic books.Additional physical formats: Print version:: No titleDDC classification: 599.3233 LOC classification: QP601 | M49 vol. 225NLM classification: W1 | QY 60.R6 G9458 1993Online resources: ScienceDirect | ScienceDirect Summary: This volume provides, for the first time, an extensive compilation of those state-of-the-art methods that have revolutionized the use of mice as an experimental system. This volume is a unique source for detailed descriptions to be used in research by both experienced and novice researchers - Germ cells and embryos; Fertilization; Gene expression: messenger RNA, reporter genes, proteins, methylation; Gene identification; Nuclear transplantation; Transgenic animals: pronuclear injection, embryonic stem cells, and gene targeting; Lineage analysis. Key Features * Contains the most up-to-date methodology as applied to mouse development * Focuses on molecular approaches to experimental mouse development * The first comprehensive source for molecular biological methods in mouse development * Many of the methods have never appeared before.
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Includes bibliographical references and indexes.

Description based on print version record.

This volume provides, for the first time, an extensive compilation of those state-of-the-art methods that have revolutionized the use of mice as an experimental system. This volume is a unique source for detailed descriptions to be used in research by both experienced and novice researchers - Germ cells and embryos; Fertilization; Gene expression: messenger RNA, reporter genes, proteins, methylation; Gene identification; Nuclear transplantation; Transgenic animals: pronuclear injection, embryonic stem cells, and gene targeting; Lineage analysis. Key Features * Contains the most up-to-date methodology as applied to mouse development * Focuses on molecular approaches to experimental mouse development * The first comprehensive source for molecular biological methods in mouse development * Many of the methods have never appeared before.

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