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Glycobiology [electronic resource] / edited by Minoru Fukuda.

Contributor(s): Fukuda, Minoru, 1945-Material type: TextTextSeries: Methods in enzymology ; v. 480.Publication details: Amsterdam, Netherlands ; Boston, Mass. : Elsevier/ Academic Press, 2010. Edition: 1st edDescription: 1 online resource (lii, 581 pages, [16] pages of plates) : illustrations (some color)Content type: text Media type: computer Carrier type: online resourceISBN: 9780123810007 (electronic bk.); 0123810000 (electronic bk.); 9780123809995 (electronic bk.); 0123809991 (electronic bk.)Subject(s): Glycomics | Carbohydrates | Metabolism | Glycomics | Carbohydrates | Glycosylation | Glycoconjugates -- Pathophysiology | Glycoconjugates -- Physiological effect | Glycoconjugates | Sugars -- Physiological effect | Science | Natural history | MEDICAL -- Biochemistry | Carbohydrates | Glycomics | MetabolismGenre/Form: Electronic books.Additional physical formats: Print version:: Glycobiology.DDC classification: 612.015 LOC classification: QP601 | .C57 2010ebOnline resources: ScienceDirect | ScienceDirect
Contents:
Auxiliary and autonomous proteoglycan signaling networks / Arye Elfenbein and Michael Simons -- Dual roles of drosophila glypican dally-like in wingless/Wnt signaling and distribution / Yihui Wu, Tatyana Y. Belenkaya, and Xinhua Lin -- Use of a phage display antibody to measure the enzymatic activity of the sulfs / Kenji Uchimura [and others] -- Glycomics profiling of heparan sulfate structure and activity / Jeremy E. Turnbull .. [et al.] -- Microbe-associated molecular patterns in innate immunity: extraction and chemical analysis of gram-negative bacterial lipopolysaccharides / Cristina De Castro .. [et al.] -- Structural and functional analysis of glycosphingolipids of Schistosoma mansoni / Irma van Die [and others] -- Biotoxicity assays for fruiting body lectins and other cytoplasmic proteins / Markus K�unzler [and others] -- Carbohydrate signaling by C-type lectin DC-SIGN affects NF-kB activity / Sonja I. Gringhuis and Teunis B.H. Geijtenbeek -- Engineered carbohydrate-recognition domains for glycoproteomic analysis of cell surface glycosylation and ligands for glycan-binding receptors / Alex S. Powlesland [and others] -- Mannose 6-phosphate receptor homology domain-containing lectins in mammalian endoplasmic reticulum-associated degradation / Nobuko Hosokawa, Koichi Kato, and Yukiko Kamiya -- Multiple functional targets of the immunoregulatory activity of galectin-1: control of immune cell trafficking, dendritic cell physiology, and T-cell fate / Dianne Cooper [and others] -- Manipulating cell surface glycoproteins by targeting N-glycan-galectin interactions / Ani Grigorian and Michael Demetriou -- Galectin-1 and HIV-1 infection / Christian St-Pierre [and others] -- The Glycomics of glycan glucuronylation in Drosophila melanogaster / Kazuhiro Aoki and Michael Tiemeyer -- Glycosyltransferases and transporters that contribute to proteoglycan synthesis in Drosophila: identification and functional analyses using the heritable and inducible RNAi system / Shoko Nishihara -- O-GlcNAc modification of the extracellular domain of notch receptors / Yuta Sakaidani, Koichi Furukawa, and Tetsuya Okajima -- Regulation of notch signaling via O-glucosylation: insights from Drosophila studies / Tom V. Lee, Hideyuki Takeuchi, and Hamed Jafar-Nejad -- O-fucosylation of thrombospondin type 1 repeats / Christina Leonhard-Melief and Robert S. Haltiwanger -- Use of glycan microarrays to explore specificity of glycan-binding proteins / David F. Smith, Xuezheng Song, and Richard D. Cummings -- Functional roles of the bisecting GlcNAc in integrin-mediated cell adhesion / Tomoya Isaji [and others] -- Lectin-based glycoproteomic techniques for the enrichment and identification of potential biomarkers / Karen L. Abbott and J. Michael Pierce -- High-throughput RNAi screening for N-glycosylation dependent loci in Caenorhabditis elegans / Weston B. Struwe and Charles E. Warren -- The acidic environment of the Golgi is critical for glycosylation and transport / Yusuke Maeda and Taroh Kinoshita -- Enzymatic synthesis of lacto-N-difucohexaose I which binds to Helicobacter pylori / Tatsuo Miyazaki [and others] -- The Drosophila 7-pass transmembrane glycoprotein BOSS and metabolic regulation: what Drosophila can teach us about human energy metabolism / Ayako Kohyama-Koganeya and Yoshio Hirabayashi.
Summary: In this 3 volume collection focusing on glycomics, readers will appreciate how such discoveries were made and how such methods can be applied for readers' own research efforts Each chapter has been designed so that enough scientific background will be given in each chapter for further development of methods by readers themselves. Useful for all levels of scientists starting from the last years of colleges, graduate students, postdoctoral fellows to professors and to all levels of scientists in research institutes including industry.
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Includes bibliographical references and indexes.

Auxiliary and autonomous proteoglycan signaling networks / Arye Elfenbein and Michael Simons -- Dual roles of drosophila glypican dally-like in wingless/Wnt signaling and distribution / Yihui Wu, Tatyana Y. Belenkaya, and Xinhua Lin -- Use of a phage display antibody to measure the enzymatic activity of the sulfs / Kenji Uchimura [and others] -- Glycomics profiling of heparan sulfate structure and activity / Jeremy E. Turnbull .. [et al.] -- Microbe-associated molecular patterns in innate immunity: extraction and chemical analysis of gram-negative bacterial lipopolysaccharides / Cristina De Castro .. [et al.] -- Structural and functional analysis of glycosphingolipids of Schistosoma mansoni / Irma van Die [and others] -- Biotoxicity assays for fruiting body lectins and other cytoplasmic proteins / Markus K�unzler [and others] -- Carbohydrate signaling by C-type lectin DC-SIGN affects NF-kB activity / Sonja I. Gringhuis and Teunis B.H. Geijtenbeek -- Engineered carbohydrate-recognition domains for glycoproteomic analysis of cell surface glycosylation and ligands for glycan-binding receptors / Alex S. Powlesland [and others] -- Mannose 6-phosphate receptor homology domain-containing lectins in mammalian endoplasmic reticulum-associated degradation / Nobuko Hosokawa, Koichi Kato, and Yukiko Kamiya -- Multiple functional targets of the immunoregulatory activity of galectin-1: control of immune cell trafficking, dendritic cell physiology, and T-cell fate / Dianne Cooper [and others] -- Manipulating cell surface glycoproteins by targeting N-glycan-galectin interactions / Ani Grigorian and Michael Demetriou -- Galectin-1 and HIV-1 infection / Christian St-Pierre [and others] -- The Glycomics of glycan glucuronylation in Drosophila melanogaster / Kazuhiro Aoki and Michael Tiemeyer -- Glycosyltransferases and transporters that contribute to proteoglycan synthesis in Drosophila: identification and functional analyses using the heritable and inducible RNAi system / Shoko Nishihara -- O-GlcNAc modification of the extracellular domain of notch receptors / Yuta Sakaidani, Koichi Furukawa, and Tetsuya Okajima -- Regulation of notch signaling via O-glucosylation: insights from Drosophila studies / Tom V. Lee, Hideyuki Takeuchi, and Hamed Jafar-Nejad -- O-fucosylation of thrombospondin type 1 repeats / Christina Leonhard-Melief and Robert S. Haltiwanger -- Use of glycan microarrays to explore specificity of glycan-binding proteins / David F. Smith, Xuezheng Song, and Richard D. Cummings -- Functional roles of the bisecting GlcNAc in integrin-mediated cell adhesion / Tomoya Isaji [and others] -- Lectin-based glycoproteomic techniques for the enrichment and identification of potential biomarkers / Karen L. Abbott and J. Michael Pierce -- High-throughput RNAi screening for N-glycosylation dependent loci in Caenorhabditis elegans / Weston B. Struwe and Charles E. Warren -- The acidic environment of the Golgi is critical for glycosylation and transport / Yusuke Maeda and Taroh Kinoshita -- Enzymatic synthesis of lacto-N-difucohexaose I which binds to Helicobacter pylori / Tatsuo Miyazaki [and others] -- The Drosophila 7-pass transmembrane glycoprotein BOSS and metabolic regulation: what Drosophila can teach us about human energy metabolism / Ayako Kohyama-Koganeya and Yoshio Hirabayashi.

In this 3 volume collection focusing on glycomics, readers will appreciate how such discoveries were made and how such methods can be applied for readers' own research efforts Each chapter has been designed so that enough scientific background will be given in each chapter for further development of methods by readers themselves. Useful for all levels of scientists starting from the last years of colleges, graduate students, postdoctoral fellows to professors and to all levels of scientists in research institutes including industry.

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