Antisense technology [electronic resource] / edited by M. Ian Phillips.

Contributor(s): Phillips, M. IanMaterial type: Text

TextSeries: Methods in enzymology ; v. 313-314.Publication details: San Diego : Academic Press, c2000. Description: 1 online resource (2 v.) : ill. (some col.)ISBN: 0121822141 (electronic bk.); 9780121822149 (electronic bk.)Subject(s): Antisense nucleic acids | Antisense RNA | Genetic engineering | Antisense Elements (Genetics) | RNA, Antisense | Antisense nucleic acids | Antisense RNA | Genetic engineeringGenre/Form: Electronic books.Additional physical formats: Print version:: Antisense technology.DDC classification: 572.8 LOC classification: QP601 | .M49 vol. 313-314QP625.N88NLM classification: W1 | QU 57Online resources: ScienceDirect

Contents:

pt. A. General methods, methods of delivery, and RNA studies -- pt. B. Applications.

Summary: Antisense technology is the ability to manipulate gene expression within mammalian cells providing powerful experimental approaches for the study of gene function and gene regulation. For example, methods that inhibit gene expression permit studies which probe the normal function of a specific product within a cell. Such methodology can be used in many disciplines such as pharmacology, oncology, genetics, cell biology, developmental biology, molecular biology, biochemistry, and neurosciences. This volume will be a truly important tool in biomedical-oriented research. The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today--truly an essential publication for researchers in all fields of life sciences.

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Includes bibliographical references and indexes.

pt. A. General methods, methods of delivery, and RNA studies -- pt. B. Applications.

Description based on print version record.

Antisense technology is the ability to manipulate gene expression within mammalian cells providing powerful experimental approaches for the study of gene function and gene regulation. For example, methods that inhibit gene expression permit studies which probe the normal function of a specific product within a cell. Such methodology can be used in many disciplines such as pharmacology, oncology, genetics, cell biology, developmental biology, molecular biology, biochemistry, and neurosciences. This volume will be a truly important tool in biomedical-oriented research. The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today--truly an essential publication for researchers in all fields of life sciences.

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