Advances in cancer research [electronic resource] . Volume 71 / edited by George Vande Woude.

Includes bibliographical references and index.

Volume 71 of Advances in Cancer Research begins with Morgan and Kastan presenting data on the roles of p53 and ATM in cell cycle progression and cell death in response to DNA damage and how this information may lead to targets for improved cancer therapies. Kok et all. Review the methodological advantages and limitations to localizing tumor suppressor genes, especially those on the short arm of chromosome 3.

Foundations in Cancer Research p53 and ATM: Cell Cycle, Cell Death, and Cancer -- Deletions of the Short Arm of Chromosome 3 in Solid Tumors and the Search for Suppressor Genes -- Mutations Predisposing to Hereditary Nonpolyposis Colorectal Cancer -- Functional Aspects of Apoptosis in Hematopoiesis and Consequences of Failure -- Cyclin-Dependent Kinase Regulation during G1 Phase and Cell Cycle Regulation by TGF-[beta] -- The Natural Somatic Mutation Frequency and Human Carcinogenesis -- CD44: Structure, Function and Association with the Malignant Process -- Human Papillomaviruses and cervical Cancer -- HER-2/neu Protein: A Target for Antigen-Specific Immunotherapy of Human Cancer.

Description based on print version record.