New transcription factors and their role in diabetes and therapy (Record no. 20922)
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| fixed length control field | 06726cam a2200745Ia 4500 |
| 001 - CONTROL NUMBER | |
| control field | ocn162130225 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | OCoLC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20141103172211.0 |
| 006 - FIXED-LENGTH DATA ELEMENTS--ADDITIONAL MATERIAL CHARACTERISTICS | |
| fixed length control field | m o d |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION | |
| fixed length control field | cr cn||||||||| |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 070802s2006 ne a ob 001 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | |
| Language of cataloging | eng |
| Transcribing agency | OPELS |
| Modifying agency | BAKER |
| -- | OPELS |
| -- | OCLCQ |
| -- | N$T |
| -- | E7B |
| -- | NRU |
| -- | OCLCQ |
| -- | REDDC |
| -- | OCLCQ |
| -- | TULIB |
| -- | OCLCO |
| -- | OCLCQ |
| -- | OPELS |
| -- | NLGGC |
| -- | CHVBK |
| 019 ## - | |
| -- | 123453129 |
| -- | 154703295 |
| -- | 647616745 |
| -- | 779917399 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9780444511584 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 044451158X |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9780080463834 (electronic bk.) |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 0080463835 (electronic bk.) |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| Canceled/invalid ISBN | 008046355X |
| 029 1# - (OCLC) | |
| OCLC library identifier | NZ1 |
| System control number | 12434453 |
| 029 1# - (OCLC) | |
| OCLC library identifier | AU@ |
| System control number | 000048130535 |
| 029 1# - (OCLC) | |
| OCLC library identifier | DEBBG |
| System control number | BV039829046 |
| 029 1# - (OCLC) | |
| OCLC library identifier | AU@ |
| System control number | 000051557986 |
| 029 1# - (OCLC) | |
| OCLC library identifier | NLGGC |
| System control number | 380877309 |
| 029 1# - (OCLC) | |
| OCLC library identifier | CHVBK |
| System control number | 166988847 |
| 029 1# - (OCLC) | |
| OCLC library identifier | CHBIS |
| System control number | 005663615 |
| 035 ## - SYSTEM CONTROL NUMBER | |
| System control number | (OCoLC)162130225 |
| Canceled/invalid control number | (OCoLC)123453129 |
| -- | (OCoLC)154703295 |
| -- | (OCoLC)647616745 |
| -- | (OCoLC)779917399 |
| 037 ## - SOURCE OF ACQUISITION | |
| Stock number | 109762:109810 |
| Source of stock number/acquisition | Elsevier Science & Technology |
| Note | http://www.sciencedirect.com |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER | |
| Classification number | QP187.3.M64 |
| Item number | A38 v.5eb |
| 060 #4 - NATIONAL LIBRARY OF MEDICINE CALL NUMBER | |
| Classification number | W1 |
| Item number | AD6823 v.5 2006 |
| 060 #4 - NATIONAL LIBRARY OF MEDICINE CALL NUMBER | |
| Classification number | WK 810 |
| Item number | N5329 2006 |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | HEA |
| Subject category code subdivision | 039050 |
| Source | bisacsh |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 616.46207 |
| Edition number | 22 |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | TEFA |
| 245 00 - TITLE STATEMENT | |
| Title | New transcription factors and their role in diabetes and therapy |
| Medium | [electronic resource] / |
| Statement of responsibility, etc. | editor, Jacob E. Friedman. |
| 250 ## - EDITION STATEMENT | |
| Edition statement | 1st ed. |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT) | |
| Place of publication, distribution, etc. | Amsterdam ; |
| -- | Boston : |
| Name of publisher, distributor, etc. | Elsevier, |
| Date of publication, distribution, etc. | 2006. |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 1 online resource (xii, 309 p.) : |
| Other physical details | ill. |
| 490 1# - SERIES STATEMENT | |
| Series statement | Advances in molecular and cellular endocrinology ; |
| Volume/sequential designation | v. 5 |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | This book contains contributions from some of the most eminent experts in the fields of genetics, biochemistry, and pathophysiology of diabetes. Through specific examples, with broad applications, this book provides a comprehensive look at how transcription factors may underline the pathogenetic mechanisms of diabetes and obesity. Volume 5 provides an overview of the status of the field, while also providing valuable information of practical utility to those who do not necessarily work in this field. The integration of basic biology with physiologically and clinically relevant proteins should provide the reader with a theoretical background to understanding the strategies for new potential therapeutic targets and their application to disease. *Applies molecular biology to transcriptional regulation of metabolism and obesity *Underscores the clinical relevance of transcription factors *Provides a valuable overview of the current status of the field. |
| 505 0# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | 1. PPARs as therapeutic targets for treating diabetes and insulin resistance -- 2. Genetic regulators of human obesity and diabetes -- 3. NF-kb, insulin resistance and the actions of salicylates -- 4. Wnt signaling and C/EBPs role in adipogenesis -- 5. Regulation of hepatic gluconeogenesis C/EPBs -- 6. Forkhead proteins and regulation of hepatic gene expression -- 7. Control of mitochondrial biogenesis through PGC-1 -- 8. Regulation of PGC-1 in humans in insulin resistance and diabetes: Functional implications -- 9. FOXC2 controls resistance to obesity and Type II diabetes -- 10. SREB-1C regulation of nutrient homeostasis and lipid accumulation -- 11. GATA proteins as molecular gatekeeprs of the adipocyte -- 12. Diabetes regulation of gene expression by CREB -- 13. Molecular etiologies of MODY and other early-onset forms of diabetes -- 14. Liver X receptors as potential drug targets for Diabetes and its disorders -- 15. The potential therapeutic use of PPAR beta/delta agonists in lipid and glucose homeostasis -- 16. Influences of new PPAR insulin sensitizers on the metabolic syndrome in Rhesus Monkeys -- 17. PPARgamma and metabolism: Insights from the study of human genetic variants. |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE | |
| Bibliography, etc | Includes bibliographical references and index. |
| 505 0# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | Transcription factor genes in type 2 diabetes / by M.N. Weedon, A.T. Hattersley & T.M. Frayling -- PPAR[gamma], a key therapeutic target in the metabolic syndrome-unique insights derived from the study of human genetic variants / by C.S. Mitchell & M. Gurnell -- PPAR[delta]: emerging therapeutic potential of novel agonists in lipid and glucose homeostasis / by U. Dressel & G.E.O. Muscat -- Liver X receptors as potential drug targets for diabetes and its disorders / by K.R. Steffenson -- SREBP-lc regulation of nutrient homeostasis and lipid accumulation / by P. Ferr�e ... [et al.] -- The adipocyte and adipose tissue as endocrine organs: impact on the insulin resistance phenotype / by R.R. Henry ... [et al.] -- FOXC2 in the adipocyte / by S. Enerb�ack -- Regulation of adipocyte differentiation and metabolism by Wnt signaling and C/EBP transcription factors / by I. Gerin, H.D. Cha & O.A. MacDougald -- GATA proteins as molecular gatekeepers of adipogenesis / by J. Tsai, Q. Tong & G.S. Hotamisligil -- Forkhead proteins and the regulation of hepatic gene expression / by A. Barthel, S. Herzig & D. Schmoll -- Disruption of CREB regulated of gene expression in diabetes / by J.E.B. Reusch, P.A. Watson & S. Pugazhenthi -- Regulation of PGC-1 in humans with insulin resistance and type 2 diabetes: functional implications / by J. Pihlajam�aki & M.E. Patti -- Hepatic CCAAT/enhancer binding protein [beta] (C/EBP[beta]): engineer of diabetes, obesity, and inflammatory disease processes / by J.M. Schroeder-Gloeckler, S.M. Rahman & J.E. Friedman -- Insulin resistance, inflammation, and the IKK/I[kappa]B/NF-[kappa]B pathway by B.A. Bhatt & R.M. O'Doherty. |
| 588 ## - SOURCE OF DESCRIPTION NOTE | |
| Source of description note | Description based on print version record. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Transcription factors. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Diabetes |
| General subdivision | Genetic factors. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Diabetes |
| General subdivision | Pathophysiology. |
| 650 #6 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Diab�ete |
| General subdivision | Physiopathologie. |
| 650 #6 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Facteurs de transcription. |
| 650 #6 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Ob�esit�e |
| General subdivision | Physiopathologie. |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | HEALTH & FITNESS |
| General subdivision | Diseases |
| -- | Diabetes. |
| Source of heading or term | bisacsh |
| 650 #4 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Diabetes Mellitus, Type 2 |
| General subdivision | Genetics. |
| 650 #4 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Diabetes mellitus, Type 2 |
| General subdivision | Physiopathology. |
| 650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Diabetes Mellitus, Type 2. |
| 650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Transcription Factors. |
| 655 #4 - INDEX TERM--GENRE/FORM | |
| Genre/form data or focus term | Electronic books. |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Friedman, Jacob E. |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY | |
| Relationship information | Print version: |
| Title | New transcription factors and their role in diabetes and therapy. |
| Edition | 1st ed. |
| Place, publisher, and date of publication | Amsterdam ; Boston : Elsevier, 2006 |
| International Standard Book Number | 044451158X |
| -- | 9780444511584 |
| Record control number | (OCoLC)84712688 |
| 830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE | |
| Uniform title | Advances in molecular and cellular endocrinology ; |
| Volume number/sequential designation | v. 5. |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Materials specified | ScienceDirect |
| Uniform Resource Identifier | <a href="http://www.sciencedirect.com/science/book/9780444511584">http://www.sciencedirect.com/science/book/9780444511584</a> |
| 938 ## - | |
| -- | Baker & Taylor |
| -- | BKTY |
| -- | 139.95 |
| -- | .00 |
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| -- | 0006308408 |
| -- | active |
| 938 ## - | |
| -- | ebrary |
| -- | EBRY |
| -- | ebr10150482 |
| 938 ## - | |
| -- | EBSCOhost |
| -- | EBSC |
| -- | 173500 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Koha item type | E(electronic)-Books |
| 994 ## - | |
| -- | C0 |
| -- | TEF |
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