Phase II conjugation enzymes and transport systems
Phase II conjugation enzymes and transport systems [electronic resource] /
Phase two conjugation enzymes and transport systems
edited by Helmut Sies, Lester Packer.
- San Diego, Calif. : Elsevier Academic Press, c2005.
- 1 online resource (xxxix, 695, [28] p. of plates) : ill.
- Methods in enzymology, v. 400 0076-6879 ; .
- Methods in enzymology ; v. 400. .
Includes bibliographical references and indexes.
This volume on conjugation enzymes and transporters serves to bring together current methods and concepts in an interesting, important and rapidly developing field of cell and systems biology. It focuses on the so-called Phase II enzymes of drug metabolism (xenobiotics), which has important ramifications for endogenous metabolism and nutrition. Also included are aspects on Phase III, transport systems. This volume of Methods in Enzymology presents current knowledge and methodology on glucuronidation, sulfation, acetylation, and transport systems in this field of research. Together with the volumes on Quinones and Quinone Enzymes (volumes 378 and 382), and on Glutathione Transferases and gamma-Glutamyl Transpeptidases (volume 401), the state of knowledge on proteomics and metabolomics of many pathways of (waste) product elimination, enzyme protein induction and gene regulation and feedback control is provided. This volume will help stimulate future investigations and speed the advance of knowledge in systems biology. *A laboratory standard for more than 40 years *Over 400 volumes strong *Also available on ScienceDirect.
0121828050 (electronic bk.) 9780121828059 (electronic bk.)
Enzymes.
Biological transport.
Metabolic conjugation.
Drugs--Metabolism.
Xenobiotics--Metabolism.
Glucuronosyltransferase--metabolism.
Acetyltransferases--metabolism.
Biological Transport--physiology.
Sulfatases--metabolism.
Xenobiotics--metabolism.
Biological transport.
Drugs--Metabolism.
Enzymes.
Metabolic conjugation.
Xenobiotics--Metabolism.
Electronic books.
QP601 / .C57 v. 400
572.74
W1 / ME9615K v.400 2005 QU 141 / P536 2005
Includes bibliographical references and indexes.
This volume on conjugation enzymes and transporters serves to bring together current methods and concepts in an interesting, important and rapidly developing field of cell and systems biology. It focuses on the so-called Phase II enzymes of drug metabolism (xenobiotics), which has important ramifications for endogenous metabolism and nutrition. Also included are aspects on Phase III, transport systems. This volume of Methods in Enzymology presents current knowledge and methodology on glucuronidation, sulfation, acetylation, and transport systems in this field of research. Together with the volumes on Quinones and Quinone Enzymes (volumes 378 and 382), and on Glutathione Transferases and gamma-Glutamyl Transpeptidases (volume 401), the state of knowledge on proteomics and metabolomics of many pathways of (waste) product elimination, enzyme protein induction and gene regulation and feedback control is provided. This volume will help stimulate future investigations and speed the advance of knowledge in systems biology. *A laboratory standard for more than 40 years *Over 400 volumes strong *Also available on ScienceDirect.
0121828050 (electronic bk.) 9780121828059 (electronic bk.)
Enzymes.
Biological transport.
Metabolic conjugation.
Drugs--Metabolism.
Xenobiotics--Metabolism.
Glucuronosyltransferase--metabolism.
Acetyltransferases--metabolism.
Biological Transport--physiology.
Sulfatases--metabolism.
Xenobiotics--metabolism.
Biological transport.
Drugs--Metabolism.
Enzymes.
Metabolic conjugation.
Xenobiotics--Metabolism.
Electronic books.
QP601 / .C57 v. 400
572.74
W1 / ME9615K v.400 2005 QU 141 / P536 2005
