GTPases regulating membrane dynamics
GTPases regulating membrane dynamics [electronic resource] /
edited by William E. Balch, Channing J. Der, Alan Hall.
- Amsterdam ; Boston : Elsevier Academic Press, c2005.
- 1 online resource (xliii, 692 p., [6] p. of plates) : ill. (some col.)
- Methods in enzymology, v. 404 0076-6879 ; .
- Methods in enzymology ; v. 404. .
Includes bibliographical references and index.
GTPases that regulate the myriad of membrane fission events that facilitate the assembly and disassembly of COPII (Sar1), COPI (ARF) and clathrin coats (dynamin) involved in exocytic and endocytic trafficking pathways and mitochrondrial organization remain a major challenge for future investigations to understand membrane architecture of eukaryotic cells. This volume of MIE provides a comprehensive set of articles describing the use and application of state-of-the-art methodologies to identify and characterize these GTPases and their rapidly expanding list of regulators and effectors. Methodologies focused on biochemical, molecular and advanced imaging techniques provide a wealth of investigational tools for those currently in the field and those entering the field. Many of the methodologies are generally applicable to study of these GTPases in vitro and in vivo to elucidate function in regulation of cell proliferation and signaling in normal tissue and in disease. *Comprehensive collection of GTPases (ARF, Sar1, Dynamin) GTPases involved in vesicle coat assembly and membrane fission *Identification and characterization of GTPase GEFs, GAPs and effectors *General methodologies to study GTPase function in vitro and in vivo.
0121828093 (electronic bk.) 9780121828097 (electronic bk.)
Enzymes.
Membrane fusion.
Membranes (Biology)
Enzymes.
Membrane fusion.
Membranes (Biology)
Enzymes.
Membrane Fusion.
Membranes.
Electronic books.
QP601 / .M49 vol. 404
572.696
W1 / ME9615K v.404 2005 QU 136 / G8953 2005
Includes bibliographical references and index.
GTPases that regulate the myriad of membrane fission events that facilitate the assembly and disassembly of COPII (Sar1), COPI (ARF) and clathrin coats (dynamin) involved in exocytic and endocytic trafficking pathways and mitochrondrial organization remain a major challenge for future investigations to understand membrane architecture of eukaryotic cells. This volume of MIE provides a comprehensive set of articles describing the use and application of state-of-the-art methodologies to identify and characterize these GTPases and their rapidly expanding list of regulators and effectors. Methodologies focused on biochemical, molecular and advanced imaging techniques provide a wealth of investigational tools for those currently in the field and those entering the field. Many of the methodologies are generally applicable to study of these GTPases in vitro and in vivo to elucidate function in regulation of cell proliferation and signaling in normal tissue and in disease. *Comprehensive collection of GTPases (ARF, Sar1, Dynamin) GTPases involved in vesicle coat assembly and membrane fission *Identification and characterization of GTPase GEFs, GAPs and effectors *General methodologies to study GTPase function in vitro and in vivo.
0121828093 (electronic bk.) 9780121828097 (electronic bk.)
Enzymes.
Membrane fusion.
Membranes (Biology)
Enzymes.
Membrane fusion.
Membranes (Biology)
Enzymes.
Membrane Fusion.
Membranes.
Electronic books.
QP601 / .M49 vol. 404
572.696
W1 / ME9615K v.404 2005 QU 136 / G8953 2005
