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Cancer and autoimmunity

Cancer and autoimmunity [electronic resource] / editors, Yehuda Shoenfeld, M. Eric Gershwin. - 1st ed. - Amsterdam ; New York : Elsevier, �2000. - 1 online resource (xix, 446 pages) : illustrations. - Autoantibody library . - Autoantibody library. .

Includes bibliographical references and index.

Of the two disciplines in parallel development for two decades, tumor immunology and transplantation immunology, the latter has thrived and has led to some of the most critical discoveries in immunobiology. The former continues to thwart both scientists and clinicians alike. The goal of immunologists in modern day research is to develop a simple and effective means to manipulate cancer in vivo, possibly encompassing several venues: identifying a phenotypic marker and the use of either active or passive immunization; include the use of passive reagents carrying "warheads" to selectively destroy cancer cells; or altering the basic process of cell survival. This excellent multidiscipline-authored volume presents a theme which has not been well described before. The papers include both basic and clinical science and range from sophisticated molecular biology to little more than phenomenology (e.g. the increased association of cancer in some autoimmune diseases and increased presentation of autoimmune phenomena in malignant condition). This, however, is state-of-the-art. This collection of themes will be of use not only to bench scientists, but also to clinicians who treat patients. The book represents progress at the cutting edge of this discipline, and points the way to further developments in the "black box" of immunology.

9780444503312 0444503315 9781435601147 (electronic bk.) 1435601149 (electronic bk.) 0080528457 9780080528458

122674:127499 Elsevier Science & Technology http://www.sciencedirect.com


Tumors--Immunological aspects.
Autoimmunity.
Tumors--Immunological aspects. Autoimmunity. Neoplasms--immunology. Autoantibodies. Autoimmunity.
MEDICAL--Oncology.
HEALTH & FITNESS--Diseases--Cancer.
Autoimmunity.
Tumors--Immunological aspects.
Kanker.
Auto-immuunziekten.
Neoplasms--immunology.


Electronic books.

QR188.6 / .C35 2000eb

616.99/4079

2000 I-181 QZ 200 / C215042 2000
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